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GGG@@@ZZZooo   !!!((,//566<=<CCCIIIOOOUUU[[[aaafgfllkqqqvvv{{{~~~~~~~~~~~}}~}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}~}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}~~}}}}~}}}~}}}~}~~}}}~~}}}}~}}}}}}}}}~~~~}~}}}~}~}~~~}~~~}}}}}~}}~~~}~~}~}~}~~~}~}}}~~~~~~~}~}}~~}}~}}~}~}}}}}}~}~}}}}~}~~~~~~~}}}~~~~}}~}~}~~~~~}}}~~~}}~~~}~~}~~~}~~~~~~~~~~~~~}~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;<;;<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<+6258050-03 6258002-03 6258003-02 6258005-00 Run Started Run StoppedCollection StartedCollection Stopped) POP7 Z-BigDyeV3Dye1Dye2Dye3Dye4Comment: ff22f2ced538484786837b9035a0d746Seq_4000SeqPop7z KB.bcpKB_3730_POP7_BDTv3.mobfalsetruefalsefalse10.00KB_3730_POP7_BDTv3.mobQUJJRgBldGRpcgAAAAED/wAcAAAACAAAAdwAAACXAAAAAP////////////////////////////// //////////////////////////////////////////////////////////////////////////// //////////////////8WS0JfMzczMF9QT1A3X0JEVHYzLmJjY0NNTlQAAAABABIAAQAAAAEAAAAB AAAAAAAAAABDTkFNAAAAAQASAAEAAAAXAAAAFwAAAIAAAAAARFlFXwAAAAEABAACAAAAAQAAAAIA AwAAAAAAAEZXT18AAAABAAIAAQAAAAQAAAAER0FUQwAAAABTSEZDAAAAAQAEAAIAAAABAAAAAgAA AAAAAAAAU0hGRAAAAAEABAACAAAAAQAAAAIAAAAAAAAAAFNIRk4AAAABAAQAAgAAAAEAAAACAAAA AAAAAABTSEZTAAAAAQAEAAIAAAABAAAAAgAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 00.000falsefalse20false510false800false25.0falsetruefalsefalse20true5502042020420falseKB.bcp# 5Prime Basecaller Paramters Seq_4000 Seq_40001LongSeq50_POP71DC_Cap96_Fill17800DC_Cap96_EPS_ARC_SELF10DC_Prep_Time600DC_Scale_Divisor2.0DC_Down_Sample1DC_Laser_Power_Setting25.0DC_RS_Binning_PatternDC_RS_NumCapsDC_RS_CSDataOven_Temperature60PreRun_Voltage15.0DC_PreRun_Time180Injection_Voltage1.5DC_Injection_Time15First_ReadOut_Time300Second_ReadOut_Time300Exposure_Time0Run_Voltage8.5Voltage_Number_Of_Steps40Voltage_Step_Interval15Voltage_Tolerance0.6Current_Stability30.0DC_Ramp_Delay600DC_Data_Delay405DC_Run_Time4000Seq50Pop7Z_4000Run_3730NHB_2018-08-03_18-47_01433130Seq1285612856_Steier_K1318_trnHjmadera96-Well K1318_G7_trnHKB_3730_POP7_BDTv3.mobSeqPop7z!#%'),.147;?CHLQV[ahq{+9GVetq\E.{tmfa^]^`dhmqv{xqjc[SLF@=:75320002468;=?ABDFHJKLLLKIGDA><:98754321000012345556679:<=?@ABCDEFGIKNQTW[_eks{/F]s{dK1AwHO\+%*j V{Fzqh`YSLGC?=;98777788765446:?ELS\fr~xpic^ZWUUUTSQONMNOQRRPNKHECB@>;851.+(%!!$(+.259=BFJMOPPPQQQRRQOLHDA>;98641.+(%"!!"#%&''''''''()+.1369<@EINRVY[^`cegiiigda\XSNIEB?=:852/,(%!                                      $(+./1247:=ADGHIJKLMOPQRQPNMLKKJHEB>;86431/,($      "&*.02468;>@BCBA?===>ADHLPTWZ]`cgkpty|  8c Kp`5sH {yy{}vmd[RLGDBA?<:76579=AEHLPUZagkmlhb[TNIGFGHIJJKKKLLMMLKHEA=:88899889:=@DGIKLOQTUVUTSTVY]`bcdgls{+;IUam|)RsqP%fO8!{k^SJB<730-*'%#""""##$$$$$"! (08=?>:4,$                                                          )4@N]m}~oaTH=3,&#! !!"#$%&()*****))(((()*+-/148;@DINRVZ]_aaa`^[XTPKE@:50-+))))**,-0369<?ACCDCBA@??>==<;:875555678888766431/,*(%#!"&)-024432/,)&$"                                                          "#%'(*+-/259<@CEFFFEEEGILNQRTTUVVWXZ[]]^]\\\\^adgijklllmnnnliea]YVTQNKHFEDEFGHJLPU[bjrzuk`VLC;3,&! #(,17>EMU]emtzztnhc^ZVROLJIIJKLMNOPQRUY_gq|%;Oar>s&|Jt|[/k^Bb,{wrmifeeffec`\YVROKGC@=;8642223568:;<=?ACEFHIJKLMMNNMLKJIHFDB@>>>>>>=<;:;;=>@BDEGHHHHFDB?<9631.,)'&&&'()**,.048;?ACFHKPV]enxztokhd`[VPJC<61-*'$"                                    @6zA AOAlKB.bcpKB_3730_POP7_BDTv3.mobtermTAGGTGCGCATGCGAATACAGTTTCATCTGTCTGCCAGTTTTCTGCAAGGTTTTCTCTTTTTTCCATTCATCATTGTTGTCTTTATTCTGACCTCCATACTTAACTTAGATCGAGATATTGGACATAGAATGCCAATCTTTAAAATAAAAAATGTAAAAAAAAAGGAGTAATACACTGTGACATGACACGTTCACTAAAAAAAAACCCTTTTGTAGCTAATCATTTATCGGCCAAATTGAAAAACTCAACACGAGGGAAGAAAAAGAAATAATAGTAACTTGGTCTCGGGCATCTACCATTATACCCACAATGATTGGCCATACAATCGCTATTCATAATGGAAAGGAACATTTACCTATTTATATAACGGACCGTATGGTGGGTCACAAATTGGGAGAATTTGCGCCAACTCTGTCTTTTACGAGAGATGCAAGAAACGATGATAAATCTCGTCGTTAAGTTCATTTCTTACACCTTATCTACTTATATACTTCTGTATTTGTGTTTAGTATACATATATACAATCTAAATATCTAAATATGTTATACAATATAAATAAATATGTATGCTATACGCAAAAAAAAATTACATTACATCAAACAAATAACAATACCCCATATCTCGCTTAAGCGAGATATGGGGTATTGTTATTTCAGGGAATTACTACATTTCTTTTACAGTTCAGATACACTAGGACAAAAGTCTTATCCATTTGTAGATGAAATCTTCCACAGCACTAGGTCTAGAGGAAAATTGTGAGCATTACGTTCATGAATAACAAAACTAGGTGCGCATGCGAATACAGTTTCATCTGTCTGCCAGTTTTCTGCAAGGTTTTCTCTTTTTTCCATTCATCATTGTTGTCTTTATTCTGACCTCCATACTTAACTTAGATCGAGATATTGGACATAGAATGCCAATCTTTAAAATAAAAAATGTAAAAAAAAAGGAGTAATACACTGTGACATGACACGTTCACTAAAAAAAAACCCTTTTGTAGCTAATCATTTATCGGCCAAATTGAAAAACTCAACACGAGGGAAGAAAAAGAAATAATAGTAACTTGGTCTCGGGCATCTACCATTATACCCACAATGATTGGCCATACAATCGCTATTCATAATGGAAAGGAACATTTACCTATTTATATAACGGACCGTATGGTGGGTCACAAATTGGGAGAATTTGCGCCAACTCTGTCTTTTACGAGAGATGCAAGAAACGATGATAAATCTCGTCGTTAAGTTCATTTCTTACACCTTATCTACTTATATACTTCTGTATTTGTGTTTAGTATACATATATACAATCTAAATATCTAAATATGTTATACAATATAAATAAATATGTATGCTATACGCAAAAAAAAATTACATTACATCAAACAAATAACAATACCCCATATCTCGCTTAAGCGAGATATGGGGTATTGTTATTTCAGGGAATTACTACATTTCTTTTACAGTTCAGATACACTAGGACAAAAGTCTTATCCATTTGTAGATGAAATCTTCCACAGCACTAGGTCTAGAGGAAAATTGTGAGCATTACGTTCATGAATAACAAAAC>ETo +4GTfq$2:FT`lx&1>JWcp| %2>KWao{ #/9ES`ju *7CR^it+8CMYdp{  ,7DO\it    ( 4 @ N Y c p |   # . : E Q ^ l x    * 5 A L Z g s  ! . 8 C P [ g s    ' 3 > I T ` l z  #.;FR]iu$1<JUan{ !-:EP[gs'4>KWbo{ #/:FS_kw!-9EQ[gs)5@MXcn| "/;FQ^kv.7COZer~%/<IValz"-;ER]hx'3ANZfq} $0<HT`ky !-:ER^jw(4ALYep| %1>GT_lx  ,9HT`kv (7AOZco{    & 2 < F P ` l { !!!"!.!5!@!N!\!h!u!!!!!!!!!!!"""")"6"B"L"Y"b"n"y""""""""""""# ##+#=#F#R#b#j#v##########$$ $$$0$8$C$R$Y$g$s$$$$$$$$$$$%%%%+%3%E%R%\%d>ETo +4GTfq$2:FT`lx&1>JWcp| %2>KWao{ #/9ES`ju *7CR^it+8CMYdp{  ,7DO\it    ( 4 @ N Y c p |   # . : E Q ^ l x    * 5 A L Z g s  ! . 8 C P [ g s    ' 3 > I T ` l z  #.;FR]iu$1<JUan{ !-:EP[gs'4>KWbo{ #/:FS_kw!-9EQ[gs)5@MXcn| "/;FQ^kv.7COZer~%/<IValz"-;ER]hx'3ANZfq} $0<HT`ky !-:ER^jw(4ALYep| %1>GT_lx  ,9HT`kv (7AOZco{    & 2 < F P ` l { !!!"!.!5!@!N!\!h!u!!!!!!!!!!!"""")"6"B"L"Y"b"n"y""""""""""""# ##+#=#F#R#b#j#v##########$$ $$$0$8$C$R$Y$g$s$$$$$$$$$$$%%%%+%3%E%R%\%d     ! !%#* 8"     "  "   " "$"$+"".&))10"'!"+)! 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3( - #(    00 1)NFN44f 89   - $ [f:;V *I#3O&*]B% (10o<0 /]e mB6u. 5 R. zP(-78u-+z p3>CU  /("62P u1H;:-" (NIrH"2IAM-U  [-D1SA--  55^(555ja7%,T14lnICGgK@C55:NNDVNooNV6jV$GGnn \GG3GGofVVVVGuJpVoVLVo\\8.D\L\GLLLLQ\|L.LLL%%I.RR: UVm R8RRRRRRVRnRRRjRRG,QTR!R RRRpRRRRRRO,d88HO#2YwaWJj?3 cWHd,Ectf`x$ _~l /["4{P4E?|1,Pp5tj0 Gp1`1]*pSx5P[\p7i012bg^ekAt]U?e=x{~8rdp'!J~P3,,dt9a  zD?o{HX}qykjTbQ2fp6BD*G.3#R!Qc$+$d:wn=XK8`oCbUI/d4-UM  "u,]\[,NOcp p o;@py&)&pp.3Wy_qmDbpU`5&D2sY[$`${9ppp2vtp"SY 7Ml'9p1:p5bpr\,%^o\`'7 j)HRH5$h  fQ?"<w5`{ [QTF+FAe[ ph_x1KvJC*A)aZQz|s8?KCo\Z"C|Y,>;TkCiZj\X\BOAQ7jCoI#ya}M?Ab/)95 0D/)=7h<v4n?$m,$)B=}juq-_F_2bBEA bWkx?'Xi9>Wn3Y-T=pDen9_^g(7`S7K"-HR6Xi_O6<awxzsnYsfK 0cP v>kth6Zh*6C_mpIEGM$uwZy?|19t8S$;/H  n1Td6k}lIRoXJ~w?g[nY B(A6GiG/TUQ7tjSbN@-<0dG8[xD-\R8OG6Rw;jGNprnkEhQCrOmFy"t ehjaQVy]s^uwp[itp/O~(h/"@lgW'+6xh[DG#s{xD[3;wcPGm6heyj*AGACGCGCGGGCGAGCCCATTACGGGAAAAAAGTGACCCCACTAAATGAAACACACGCCAAGCTACCCGCGGCACAACCCACAAGAGAGCCGGAGTGATGAGGCAAAGCGCTCTCCCTCCCCCTTACCCGGAAGGGGACCGTTGTGGGGTGTACGGCTTGGCCCTTCCACGCCATGGAAACTCGCGGGGTGGGCAACCCCTTTTCAATGGAGTGGAACCCAACCAAGATCCTACGGGGAGCTGGGAGCCGTAATATTGCTCGGCGACTCCTCATTGCCGGCAAATCTTATTGGACGATCCATACGGACAGGGAGCGTTGATCTACGATTTCGAGTCATCAACGGGAATTTCAGCCTTATAGATGTGCGAAACTACAGCTTGTCTATCATTTAAAAATACGAAACGATGGCACTATCACCACCAATAGCTGTTCGCCCGGAGGAGCCCCGAAGACGCGGTCACGAGGAGGAGCTCGTCCCAACGAAGTGGGGAGCAACCCCGCCCAGAGCAGTACACAGGGACACCGAAGTCCTATCGCCAGGTGCTACTGTACAGGGCTCGCGAACGGCGGCAGGCACCGCCGTCTCAGGTGAGGCCTCGCGCTGCTTTGTACTTAACATCTCGCTGAGGAGAGAGGTGTCCAATAGTGCTACCAGATAGTGGTTCTGCAGGTCGCCGGCAACGCATACACGGCCCGAGGGGACTGATGTACACGTAGTTAAGGCATCCTAGAGTTGGGTCTGTATAGCCGGCTAGTGAGAACAACGCAAATGTCTATCACGGGABCPFileName=KB.bcp;AnalyzerVersion=KB 1.4.1.8;MobilityFileName=KB_3730_POP7_BDTv3.mob;StartPoint=0;BaseOneLocation=0;StopPoint=0;StopAtPCRStop=0;AverageSpacing=0;ProcessedDataProfile=0;StopAfterNumBases=0;MaxBasesToCall=800;CallMixedBases=0;SecondaryPeakThreshold=25;NCallQvThreshold=0;StopAfterNumNs=0;MaxNumNs=20;StopAfterNumNsInXBases=0;NumNsPerXBaseInterval=5;XBaseInterval=10; KB 1.4.1.82018-08-03 20:18:42 -04:00AEPt3AEPt3APFN APXV2APrN ‡APrV1APrX}}ARTNASPFASPtASPtB1PtB1PtBCTSLBufT(PYCTID+CTNM1CTOwICTTL TCpEPDATA3gDATA3ghDATA3gЪDATA3g8DATA(P^DATA(PDATA(PDATA(PNDATA %xJDATA %xJ/DATA %xJzDATA %xJŧDCHTDSamDySN 5Dye#DyeN@DyeNEDyeNJDyeNODyeWDyeW8DyeWSDyeWgEPVt!4EVNT EVNT EVNTEVNTFWO_GATCGTyp!!HCFGCEHCFGHCFGHCFG==InScInVtLANE3LAST~~KLIMS!!]LNTD2LsrPaMCHNMODF ~MODL3730NAVGNLNE`NOISP1AM"/|P1RL")ZP1WD"5P2AM"AP2BAHP2RL";PBASPBASPCON&IPCON#8PDMFPDMFPLOC"PLOC"PSZE`PTYPQPXLBRGNm#RMXV1RMdN  RMdV1RMdXRPrNRPrV1RUND RUND RUND RUND RUNT /$RUNT :RUNT 9RUNT $Rate RunN""S/N%SCAN3SMED SMLtSMPLSPACAxSPACSPACAxSVER4.0SVER LSVER,,Scal@Scan3TUBEG7Tmpr<UserphARphCHphDYbigphQLcphTRphTR1This is the confidence range *ABI_Limits..FVocAEPt3AEPt3APFN APXV2APrN ‡APrV1APrX}}ARTNASPFASPtASPtB1PtB1PtBCTSLBufT(PYCTID+CTNM1CTOwICTTL TCpEPDATA3gDATA3ghDATA3gЪDATA3g8DATA(P^DATA(PDATA(PDATA(PNDATA %xJDATA %xJ/DATA %xJzDATA %xJŧDCHTDSamDySN 5Dye#DyeN@DyeNEDyeNJDyeNODyeWDyeW8DyeWSDyeWgEPVt!4EVNT EVNT EVNTEVNTFTabZFVocZFWO_GATCFeat//ZGTyp!!HCFGCEHCFGHCFGHCFG==InScInVtLANE3LAST~~KLIMS!!]LNTD2LsrPaMCHNMODF ~MODL3730NAVGNLNE`NOISP1AM"/|P1RL")ZP1WD"5P2AM"AP2BAHP2RL";PBASPBASPCON&IPCON#8PDMFPDMFPLOC"PLOC"PSZE`PTYPQPXLBRGNm#RMXV1RMdN  RMdV1RMdXRPrNRPrV1RUND RUND RUND RUND RUNT /$RUNT :RUNT 9RUNT $Rate RunN""S/N%SCAN3SMED SMLtSMPLSPACAxSPACSPACAxSVER4.0SVER LSVER,,Scal@Scan3TUBEG7Tmpr<UserphARphCHphDYbigphQLcphTRphTR8Bb:({.X|L=6XO?Tve!@.%J^K'p=mjzs,t5/`3T6YJ:0/.p9;4^;5s#oC&Opau_l_e5 }37Rgx|ff[`#|D5x_7&OMb'~6/lD-b)jJJTMF4Fi%P p'Icf]4'Uw\Pcc{\A_}$A>AR5Z(yHPx%bg*p/YgnP:Y'w(nZc:o2t;1"[\jxUT,Et/;k$;~6>udrVbH`6@v0kc V&Ip?H^Po)Gr(K.L-[DW[Zeh&0w#j'"LAX;:bz]QyQ]bxd$XF$~8+!3@*7_6SvrsPoIXz7_lnqR9vC.Vq`A #pJE?RVuU$HTl:h~6O$@v=aiBx[FohiXN"}a8rOrm>vdAVs+ 4,kG<;sm2J*7k'}&8)TK7kx`rxP!t p7Zf_@72tX>VS)TKQoB+BhwD~ '(CwM@B8{A)PS_W .Nio8m*1fCy]_^avep"iK]0T;7[3VT%7;H{Y+]B7b~;HnkKuaXj`Q Dx6m}>7:I12 d+[Y5xo|[Ez1{zK90l_v]M;~6bI.J:*yEwiOOd&79?Ou4[Y{zsyN}@*ohj4TIx*&`_M%Y_bO?C!.tk,8K%}jxz)>`VWYhY8|kRYN4+HmLOKrPkWE-K|ki^jAAQ`lNaKjZD(Z=c':Z^mDt4)TuTF}wKy3of)`|8&kS2BjrP}6YH4HUXYnuPQh^fP%4X+*flT)FTX>EbrB%P^gWT|0\d&nPl'Z9dp"iK]|UKo9UC|T[[66`aD/z x:H-p@~KCozPk&OE6OLiE8nZDKAEPt3AEPt3APFN APXV2APrN ‡APrV1APrX}}ARTNASPFASPtASPtAUDTjji B1PtB1PtBCTSLBufT(PYCTID+CTNM1CTOwICTTL TCpEPDATA3gDATA3ghDATA3gЪDATA3g8DATA(P^DATA(PDATA(PDATA(PNDATA %xJDATA %xJ/DATA %xJzDATA %xJŧDCHTDSamDySN 5Dye#DyeN@DyeNEDyeNJDyeNODyeWDyeW8DyeWSDyeWgEPVt!4EVNT EVNT EVNTEVNTFTabZFVocZFWO_GATCFeat//ZGTyp!!HCFGCEHCFGHCFGHCFG==InScInVtLANE3LAST~~KLIMS!!]LNTD2LsrPaMCHNMODF ~MODL3730NAVGNLNE`NOISP1AM"/|P1RL")ZP1WD"5P2AM"AP2BAHP2RL";PBASPBASPCON&IPCON#8PDMFPDMFPLOC"PLOC"PSZE`PTYPQPXLBRGNm#RMXV1RMdN  RMdV1RMdXRPrNRPrV1RUND RUND RUND RUND RUNT /$RUNT :RUNT 9RUNT $Rate RunN""S/N%SCAN3SMED SMLtSMPLSPACAxSPACSPACAxSVER4.0SVER LSVER,,Scal@Scan3TUBEG7Tmpr<UserphARphCHphDYbigphQLcphTRphTR